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Med. Pr. 2002;53(2)

Usefulness of troponin i determination in assessing cardiac damage in acute carbon monoxide poisoning

Wartość oznaczania troponiny i w diagnostyce uszkodzenia mięśnia sercowego w przebiegu ostrego zatrucia tlenkiem węgla

T. Wocka-Marek, J. Kłopotowski, M. Kicka, P. Wylężek, J. Niedziela-Marx, U. Zygan

Abstract

Tissue hypoxia in carbon monoxide poisoning is often responsible for cardiac damage that is not always registered in ECG recordings. It is therefore necessary to look for biochemical markers of this damage. Troponin I, the protein not detected in serum of healthy people meets these criteria as its presence proves the cardiac damage.
The aim of this paper was to evaluate the usefulness of troponin I determination in diagnosing cardiac damage in acute carbon monoxide poisoning. The study was performed in a group of 44 patients treated because of carbon monoxide poisoning. In addition,other biochemical markers of cardiac damage were determined.
The results of the study showed that of the 44 cases of carbon monoxide poisoning, only in 16 patients troponin I was not found in serum. The level of troponin I was increased in all cases with ECG changes,but also in 13 patients with normal ECG.

Key words

troponin I, acute carbon monoxide poisoning