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Med. Pr. 2005;56(1)

Coexistence of pneumoconiosis with myelodysplastic syndrome in a coal miner occupationally exposed to coal dust

Przypadek pylicy płuc współistniejący z zespołem mielodysplastycznym u górnika narażonego na pył węglowy

Ryszard Andrzejak1, Małgorzata Poręba2, Rafał Poręba1, Bogusław Beck1, Aleksandra Steinmetz-Beck1, Kazimierz Kuliczkowski2 1 Z Katedry i Kliniki Chorób Wewnętrznych, Zawodowych i Nadciśnienia Tętniczego 2 Z Katedry i Kliniki Hematolologii, Nowotworów Krwi i Transplantacji Szpiku Akademii Medycznej we Wrocławiu

Abstract

Pneumoconiosis is the most common occupational disease of the respiratory system. The aim of this paper is presentation of case of pneumoconiosis coexisting with myelodysplastic syndrome in a former coal miner occupationally exposed to coal dust. In a mineral coal miner, aged 56 year, with a 15-year duration of work underneath, suffering from pneumoconiosis, pancytopenia was detected. He was admitted to the hospital, where myelodysplastic syndrome was diagnosed. The patientśs condition was gradually worsening, even though chemotherapy was applied, he died from thrombocytopenia manifested by bleeding from the digestive tract in a relatively short time since diagnosis. The presented case seems to be interesting not only in view of possible development of pneumoconiosis as a result of occupational exposure to coal dust, typical in this case, but also in view of the occurrence of clonal disease of blood several years after cessation of exposure.

Key words

myelodysplastic syndrome, pneumoconiosis, coal dust